GSK329

Names

[ Name ]:
GSK329

Biological Activity

[Description]:

GSK329 is a potent and selective diarylurea inhibitor of the cardiac-specific kinase TNNI3K. GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[Target]

TNNI3K[1]

[References]

[1]. Patterson JR, et, al. Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf. J Med Chem. 2021 Nov 11;64(21):15651-15670.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₄Cl₂F₃N₅O₂

[ Molecular Weight ]:
472.25

Related Compounds

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