Nilotinib D6

Names

[ Name ]:
Nilotinib D6

Biological Activity

[Description]:

Nilotinib D6 (AMN107 D6) is a deuterium labeled Nilotinib. Nilotinib is an orally available Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl

Signaling Pathways >> Autophagy >> Autophagy

[References]

[1]. Weisberg E, et al. Beneficial effects of combining nilotinib and imatinib in preclinical models of BCR-ABL+ leukemias. Blood. 2007 Mar 1;109(5):2112-20.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₁₆D₆F₃N₇O

[ Molecular Weight ]:
535.55

Related Compounds

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