NG,NGμ-Dimethyl-L-arginine di(p-hydroxyazobenzene-pμ-sulfonate) salt

Names

[ Name ]:
NG,NGμ-Dimethyl-L-arginine di(p-hydroxyazobenzene-pμ-sulfonate) salt

[Synonym ]:
SDMA
N5-(N,N'-Dimethylcarbamimidoyl)-L-ornithine - 4-[(E)-(4-hydroxyphenyl)diazenyl]benzenesulfonic acid (1:2)
I166811
L-Ornithine, N5-[(Z)-(methylamino)(methylimino)methyl]-, compd. with 4-[(E)-2-(4-hydroxyphenyl)diazenyl]benzenesulfonic acid (1:2)

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₃₈N₈O₁₀S₂

[ Molecular Weight ]:
758.82

[ Exact Mass ]:
758.215210

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2.

J. Biol. Chem. 290 , 16723-43, (2015)

Human protein arginine methyltransferase (PRMT) 9 symmetrically dimethylates arginine residues on splicing factor SF3B2 (SAP145) and has been functionally linked to the regulation of alternative splic...

PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145.

Nat. Commun. 6 , 6428, (2015)

The human genome encodes a family of nine protein arginine methyltransferases (PRMT1-9), whose members can catalyse three distinct types of methylation on arginine residues. Here we identify two splic...

Organic anion transporting polypeptides 1B1 and 1B3 play an important role in uremic toxin handling and drug-uremic toxin interactions in the liver.

J. Pharm. Pharm. Sci. 17(4) , 475-84, (2015)

Organic anion-transporting polypeptide (OATP) 1B1 and OATP1B3 contribute to hepatic uptake of numerous drugs. Thus, reduced OATP1B1 and OATP1B3 activity in chronic kidney disease (CKD) may have a majo...