AZD 3676

Names

[ Name ]:
AZD 3676

Biological Activity

[Description]:

A novel potent, combined serotonin 5-HT1A and 5-HT1B receptor antagonist with Ki of 0.13 and 2.4 nM in brain homogenates, respectively; shows preclinical properties consistent with CNS drug potential, including nanomolar receptor affinity and efficacy in rodent models of learning and memory, shows the potential for the treatment of cognitive impairment in Alzheimer's disease.

[References]

References 1. Varnäs K, et al. J Pharmacol Exp Ther. 2016 Sep;358(3):464-71. View Related Products by Target Histamine Receptor

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₆N₄O₂

[ Molecular Weight ]:
378.476

Related Compounds

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