S-230

Names

[ Name ]:
S-230

Biological Activity

[Description]:

OXE-R antagonist S-230 is a highly potent antagonist of oxoeicosanoid receptor (OXE receptor) with IC50 of 0.12 nM, inhibits 5-oxo-ETE-induced calcium mobilization in human neutrophils.

[References]

References 1. Cossette C, et al. J Med Chem. 2016 Nov 23;59(22):10127-10146. 2. Chourey S, et al. J Med Chem. 2018 Jul 4. doi: 10.1021/acs.jmedchem.8b00154. View Related Products by Target Other Targets

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₈ClNO₃

[ Molecular Weight ]:
377.909

Related Compounds

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