VIP Antagonist

Names

[ Name ]:
VIP Antagonist

[Synonym ]:
VIP ANTAGONIST

Biological Activity

[Description]:

VIPhyb (compound VIPhyb) is a vasoactive intestinal polypeptide (VIP) receptor antagonist that can be used in the study of cancers such as non-small cell lung cancer (NSCLC)[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Moody TW, et al. (Stearyl, Norleucine17)VIP hybrid antagonizes VIP receptors on non-small cell lung cancer cells. Life Sci. 1997;61(17):1657-66.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅₄H₂₅₇N₄₉O₄₀S

[ Molecular Weight ]:
3467.06

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

VIP boosts regulatory T cell induction by trophoblast cells in an in vitro model of trophoblast-maternal leukocyte interaction.

J. Leukoc. Biol. 98 , 49-58, (2015)

Inducible regulatory T cells (Tregs) exert a timely and efficient immunosuppressive action at the critical peri-implantation stage essential for maternal tolerance to the conceptus. Vasoactive intesti...

Glucagon-like peptides 1 and 2 and vasoactive intestinal peptide are neuroprotective on cultured and mast cell co-cultured rat myenteric neurons.

BMC Gastroenterol. 12 , 30, (2012)

Neuropathy is believed to be a common feature of functional and inflammatory intestinal diseases. Vasoactive intestinal peptide (VIP) is an acknowledged neuroprotective agent in peripheral, including ...

Vasoactive intestinal polypeptide antagonists attenuate vagally induced tachycardia in the anesthetized dog.

Am. J. Physiol. 269(4 Pt 2) , H1467-72, (1995)

We used three vasoactive intestinal polypeptide (VIP) antagonists, VIP-(10-28), [p-Cl-D-Phe6,Leu17]VIP, and NT-VIP, to evaluate the role of VIP as a mediator of vagally induced tachycardia in chloralo...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.