Vomicine

Names

[ CAS No. ]:
125-15-5

[ Name ]:
Vomicine

[Synonym ]:
Vomicin
12-Hydroxy-N-methylpseudostrychnine
(4aR,6aS,12aS,12bR,12cS)-10-hydroxy-15-methyl-4a,5,12,12a,12b,12c-hexahydro-11H-6a,4-(ethanoiminomethano)-1-oxa-10b-azacyclohepta[1,2,3-cd]fluoranthene-6,11(2H)-dione
(1S,10S,22R,23R,24S)-15-Hydroxy-4-methyl-9-oxa-4,13-diazahexacyclo[11.6.5.0.0.0.0]tetracosa-6,14,16,18-tetraene-12,20-dione
16,19-Secostrychnidine-10,16-dione, 4-hydroxy-19-methyl-
Strychnicine
4-Hydroxy-19-methyl-16,19-secostrychnidine-10,16-dione
16,19-Secostrychnidine-10,16-dione,4-hydroxy-19-methyl
12H-6a,4-(Ethanoiminomethano)indolo[3,2,1-ij]oxepino[2,3,4-de]quinoline-6,12(2H)-dione, 4a,5,13,13a,13b,13c-hexahydro-10-hydroxy-16-methyl-, (4aR,6aS,13aS,13bR,13cS)-
4-hydroxy-19-methyl-16,19-seco-strychnidine-10,16-dione
4-hydroxy-icajine
Vomicine
4-hydroxy-19-methyl-16,19-seco-strychnidin-10,16-dione

Biological Activity

[Description]:

Vomicine, an alkaloid isolated from seeds of S. nux-vomica, shows antidiabetic activity[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Bhati R, et al. Strychnos nux-vomica seeds: Pharmacognostical standardization, extraction, and antidiabetic activity. J Ayurveda Integr Med. 2012 Apr;3(2):80-4.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
636.9±55.0 °C at 760 mmHg

[ Melting Point ]:
286-290℃ (dec.)

[ Molecular Formula ]:
C₂₂H₂₄N₂O₄

[ Molecular Weight ]:
380.437

[ Flash Point ]:
339.0±31.5 °C

[ Exact Mass ]:
380.173615

[ PSA ]:
70.08000

[ LogP ]:
0.47

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.699

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.