E3ligaseLigand-LinkerConjugates33Hydrochloride

Names

[ Name ]:
E3ligaseLigand-LinkerConjugates33Hydrochloride

Biological Activity

[Description]:

E3 ligase Ligand-Linker Conjugates 33 Hydrochloride incorporates a cIAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 33 can be used to design PROTAC degrader[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[Target]

cIAP1

[References]

[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₅H₄₄ClN₃O₇

[ Molecular Weight ]:
654.19

Related Compounds

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