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Trigoxyphin A

Names

[ CAS No. ]:
1236874-00-2

[ Name ]:
Trigoxyphin A

[Synonym ]:
(1R,2R,6S,7S,8R,10S,11S,12R,14S,16S,17S,18R)-6,7-Dihydroxy-16-isopropenyl-4,8,18-trimethyl-5-oxo-14-phenyl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl benzoa te
6H-2,8b-Epoxyoxireno[6,7]azuleno[5,4-e]-1,3-benzodioxol-6-one, 10-(benzoyloxy)-3a,3b,3c,4a,5,5a,8a,9,10,10a-decahydro-5,5a-dihydroxy-4a,7,9-trimethyl-10a-(1-methylethenyl)-2-phenyl-, (2S,3aR,3bS,3cS,4aR,5S,5aS,8aR,8bR,9R,10S,10aS)-

Biological Activity

[Description]:

Trigoxyphin A is a oxygenated daphnane-type diterpenoids. Trigoxyphin A exhibites strong cytotoxic activity against HL60 and A549 with IC50s of 0.27 and 7.5 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Lin BD, et al. Trigoxyphins A-G: diterpenes from Trigonostemon xyphophylloides. J Nat Prod. 2010 Jul 23;73(7):1301-5.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Melting Point ]:
211℃ (Decomposition)

[ Molecular Formula ]:
C34H34O9

[ Molecular Weight ]:
586.63

[ Exact Mass ]:
586.220276

[ LogP ]:
8.11

[ Index of Refraction ]:
1.671

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds