AK-778-XXMU

Names

[ Name ]:
AK-778-XXMU

Biological Activity

[Description]:

AK-778-XXMU is a potent inhibitor of DNA Binding 2 (ID2) antagonist with a KD of 129 nM. AK-778-XXMU can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and more importantly, slow down the tumor growth[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Zhong G, et al. Discovery of novel ID2 antagonists from pharmacophore-based virtual screening as potential therapeutics for glioma. Bioorg Med Chem. 2021;49:116427.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₁₇ClN₂O₃

[ Molecular Weight ]:
392.83

Related Compounds

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