DT-2

Names

[ CAS No. ]:
1220985-78-3

[ Name ]:
DT-2

Biological Activity

[Description]:

DT-2 is a potent and selective inhibitor of the cGMP-dependent protein kinase (PKG). DT-2 inhibits PKG catalyzed phosphorylation (Ki: 12.5 nM)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Pinkse MWH, et al. Mode of action of cGMP-dependent protein kinase-specific inhibitors probed by photoaffinity cross-linking mass spectrometry. J Biol Chem. 2009 Jun 12;284(24):16354-16368.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂₂H₂₂₃N₅₃O₂₃

[ Molecular Weight ]:
2800.42

Related Compounds

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