Benzalacetone
Names
[ CAS No. ]:
122-57-6
[ Name ]:
Benzalacetone
[Synonym ]:
FEMA 2881
Benzylideneacetone
methyl styryl ketone
Benzalaceton
4-Phenylbutenone
4-Phenyl-3-Buten-2-One
1-methyl-3-phenyl-2-propen-1-one
EINECS 204-555-1
benzylidene
Methylstyrylketon
MFCD00008779
METHYLSTYRYL
BENZALAOETONE
4-Phenylbut-3-en-2-one
Benzalacetone
ACETOCINNAMONE
Benzylideneacetone,Methyl styryl ketone
Benzylidene acetone
Benzal Acetone
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
260.8±9.0 °C at 760 mmHg
[ Melting Point ]:
39-42 °C(lit.)
[ Molecular Formula ]:
C10H10O
[ Molecular Weight ]:
146.186
[ Flash Point ]:
65.6±0.0 °C
[ Exact Mass ]:
146.073166
[ PSA ]:
17.07000
[ LogP ]:
2.17
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.563
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EN0330000
- CHEMICAL NAME :
- 3-Buten-2-one, 4-phenyl-
- CAS REGISTRY NUMBER :
- 122-57-6
- BEILSTEIN REFERENCE NO. :
- 0742046
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C10-H10-O
- MOLECULAR WEIGHT :
- 146.20
- WISWESSER LINE NOTATION :
- 1V1U1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 11,1021,1973
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- REFERENCE :
- JSCCA5 Journal of the Society of Cosmetic Chemists. (Soc. of Cosmetic Chemists, 1995 Broadway, Suite 1701, New York, NY 10023) V.1- 1947- Volume(issue)/page/year: 28,357,1977 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2031 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Vascular - regional or general arteriolar or venous dilation Skin and Appendages - hair
- REFERENCE :
- EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0391-1194
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1210 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,617,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 112 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,617,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83179 No. of Facilities: 41 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 550 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83179 No. of Facilities: 196 (estimated) No. of Industries: 7 No. of Occupations: 10 No. of Employees: 5458 (estimated) No. of Female Employees: 2178 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H317
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R36/37/38;R42/43
[ Safety Phrases ]:
S7-S26-S36/37/39-S45-S37/39-S24-S36/37-S22
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
EN0330050
[ HS Code ]:
29143900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914399090
[ Summary ]:
2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
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To investigate the enzymatic aldol reaction between acetone as a donor and 4-hydroxybenzaldehyde as a receptor to generate 4-(4-hydroxyphenyl)-but-3-ene-2-one or 4-hydroxybenzylidene acetone, the dire...