Fmoc-Pro-OH-13C5,15N

Names

[ Name ]:
Fmoc-Pro-OH-13C5,15N

[Synonym ]:
Fmoc-Pro-OH-13C5,15N
L-Proline-13C5,15N,N-Fmoc derivative

Biological Activity

[Description]:

Fmoc-Pro-OH-13C5,15N is a 15N-labeled and 13C-labled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methioni

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-251.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-251.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅₁₃C₅H₁₉₁₅NO₄

[ Molecular Weight ]:
343.33

[ Exact Mass ]:
343.14500

[ PSA ]:
66.84000

[ LogP ]:
3.42240

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport