Desmethyl Erlotinib-d4
Names
[ CAS No. ]:
1216420-11-9
[ Name ]:
Desmethyl Erlotinib-d4
Biological Activity
[Description]:
Desmethyl Erlotinib-d4 (OSI-420-d4 free base) is the deuterium labeled Desmethyl Erlotinib. Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor[1][2].
[Related Catalog]:
[In Vitro]
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C21H17D4N3O4
[ Molecular Weight ]:
383.43