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HPK1-IN-8

Names

[ CAS No. ]:
1214561-09-7

[ Name ]:
HPK1-IN-8

Biological Activity

[Description]:

HPK1-IN-8 is an allosteric, inactive conformation-selective inhibitor of full-length HPK1.

[Related Catalog]:

Signaling Pathways >> MAPK/ERK Pathway >> MAP4K
Research Areas >> Cancer

[References]

[1]. Wang W, et al. Discovery of an Allosteric, Inactive Conformation-Selective Inhibitor of Full-Length HPK1 Utilizing a Kinase Cascade Assay. Biochemistry. 2021 Oct 19;60(41):3114-3124.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H17FN6O2S

[ Molecular Weight ]:
412.44

Related Compounds