3,6-Dihydroxy-9H-xanthen-9-one

Names

[ Name ]:
3,6-Dihydroxy-9H-xanthen-9-one

[Synonym ]:
9H-Xanthen-9-one,1,7-dihydroxy
F0349-4255
3,6-Dihydroxy-xanthen-9-one

Biological Activity

[Description]:

3,6-Dihydroxyxanthone (compound 3) is a xanthone derivatives. 3,6-Dihydroxyxanthone (compound 3) has anticancer activity. 3,6-Dihydroxyxanthone (compound 3) can be used for cancer research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

3,6-Dihydroxyxanthone (compound 3) (3.906-1000 µg/mL; 24 hours) exhibits cytotoxic activity against WiDR and Vero cell lines with IC50 values of 785.58 and 1280.9 µM[1]. Cell Cytotoxicity Assay[1] Cell Line: WiDR and Vero cell lines Concentration: 3.906, 7.813, 15.625, 31.25, 62.5, 125, 250 and 500 µg/mL (WiDR cell line)7.813, 15.625, 31.25, 62.5, 125, 250, 500 and 1000 µg/mL (Vero cell line) Incubation Time: 24 hours Result: Inhibited cell activity and with IC50 values of 785.58 and 1,280.9 µM for WiDR and Vero cell lines.

[References]

[1]. Miladiyah I, et, al. Biological activity, quantitative structure-activity relationship analysis, and molecular docking of xanthone derivatives as anticancer drugs. Drug Des Devel Ther. 2018 Jan 15;12:149-158.

Chemical & Physical Properties

[ Density]:
1.3036 g/cm3

[ Boiling Point ]:
330 °C

[ Melting Point ]:
395 °C

[ Molecular Formula ]:
C₁₃H₈O₄

[ Molecular Weight ]:
228.20000

[ Exact Mass ]:
228.04200

[ PSA ]:
70.67000

[ LogP ]:
2.35740

Safety Information

[ HS Code ]:
2932999099

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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