Jarin-1

Jarin-1 is the first small-molecule inhibitor of JAR1 (IC50=3.8 uM) that inhibits jasmonate responses in Arabidopsis thaliana; impairs the activity of JA-Ile synthetase, thereby preventing the synthesis of the active hormone, JA-Ile, whereas closely related enzymes are not affected; A useful chemical tool in search for missing regulatory components and further dissection of the complex jasmonate signaling networks.

References 1. Meesters C, et al. Nat Chem Biol. 2014 Oct;10(10):830-6. View Related Products by Target Other Targets