5-chlorodibenzosuberane
Names
[ CAS No. ]:
1210-33-9
[ Name ]:
5-chlorodibenzosuberane
[Synonym ]:
Dibenzosuberyl Chloride
MFCD00003592
11-chloro-6,11-dihydro-5H-dibenzo[2,1-b:2',1'-f][7]annulene
5-Chloro-10,11-dihydro-5H-dibenzo[a,d]cycloheptene
EINECS 214-910-2
5-Chlorodibenzosuberane
Chemical & Physical Properties
[ Density]:
1.19g/cm3
[ Boiling Point ]:
321.7ºC at 760mmHg
[ Melting Point ]:
106-107 °C(lit.)
[ Molecular Formula ]:
C15H13Cl
[ Molecular Weight ]:
228.71700
[ Flash Point ]:
136.6ºC
[ Exact Mass ]:
228.07100
[ LogP ]:
4.11340
[ Vapour Pressure ]:
0.001mmHg at 25°C
[ Index of Refraction ]:
1.627
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HO8302000
- CHEMICAL NAME :
- 5H-Dibenzo(a,d)cycloheptene, 10,11-dihydro-5-chloro-
- CAS REGISTRY NUMBER :
- 1210-33-9
- BEILSTEIN REFERENCE NO. :
- 0612280
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C15-H13-Cl
- MOLECULAR WEIGHT :
- 228.73
- WISWESSER LINE NOTATION :
- L C676&T&J BG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02165
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
3261
[ WGK Germany ]:
3
[ RTECS ]:
HO8302000
[ Packaging Group ]:
II
[ Hazard Class ]:
8
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Med. Chem. 35 , 2481, (1992)
A series of 70 triazine derivatives have been synthesized and tested for their capacity to modulate multidrug resistance (MDR) in DC-3F/AD and KB-A1 tumor cells in vitro, in comparison with verapamil ...