Withangulatin A

Names

[ CAS No. ]:
120824-03-5

[ Name ]:
Withangulatin A

[Synonym ]:
withagulatin A

Biological Activity

[Description]:

Withangulatin A is a selective cyclooxygenase-2 (COX-2) inhibitor. Withangulatin A can be isolated from Physalis angulata L. Withangulatin A has anti-tumor, trypanocidal activity and anti-inflammatory function[1].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Immunology/Inflammation >> COX

[References]

[1]. Lijuan Sun, et al. Anti-inflammatory function of Withangulatin A by targeted inhibiting COX-2 expression via MAPK and NF-kappaB pathways. J Cell Biochem. 2010 Feb 15;109(3):532-41.  

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
699.4ºC at 760mmHg

[ Molecular Formula ]:
C30H38O8

[ Molecular Weight ]:
526.61800

[ Flash Point ]:
227.7ºC

[ Exact Mass ]:
526.25700

[ PSA ]:
122.66000

[ LogP ]:
2.95710

[ Vapour Pressure ]:
1.29E-22mmHg at 25°C

[ Index of Refraction ]:
1.606


Related Compounds

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