ARRY-502

Names

[ CAS No. ]:
1202891-16-4

[ Name ]:
ARRY-502

[Synonym ]:
2H-1-Benzopyran-4-carboxylic acid, 6-chloro-7-[4-[[[2-(4-chloro-2-methoxyphenyl)ethyl]amino]carbonyl]phenoxy]-3,4-dihydro-, (4S)-
(4S)-6-Chloro-7-(4-{[2-(4-chloro-2-methoxyphenyl)ethyl]carbamoyl}phenoxy)-4-chromanecarboxylic acid

Biological Activity

[Description]:

ARRY-502 is an orally bioavailable, potent and selective antagonist of the prostaglandin D2 receptor (CRTh2) for treatment of mild to moderate Th2-driven asthma. Asthma Phase 2 Discontinued

[References]

References View Related Products by Target Prostaglandin Receptor Asthma

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
686.1±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₆H₂₃Cl₂NO₆

[ Molecular Weight ]:
516.370

[ Flash Point ]:
368.8±31.5 °C

[ Exact Mass ]:
515.090271

[ LogP ]:
4.95

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.619

Related Compounds

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