4-Bromocinnamic acid

Names

[ Name ]:
4-Bromocinnamic acid

[Synonym ]:
3-(4-Bromophenyl)acrylic acid
TRANS-4-BROMOCINNAMIC ACID
2-Propenoic acid, 3-(4-bromophenyl)-, (2E)-
4-BROMO CINNAMIC ACID
4-Bromocinnamic Acid,Predominantly Trans
(2E)-3-(4-Bromophenyl)acrylic acid
2-Propenoic acid, 3-(4-bromophenyl)-
4-bromocinnacid
4-bromo-trans-cinnamic acid
3-(4-bromophenyl)propanoic acid
4-Bromocinnamicacid
(E)-3-(3-bromophenyl)acrylic acid
MFCD00004394
(2E)-3-(4-bromophenyl)prop-2-enoic acid
2-PROPENOICACID, 3-(4-BROMOPHENYL)-
RARECHEM BK HD C006
3-(4-BROMO-PHENYL)-ACRYLICACID
BROMOCINNAMIC ACID,4
EINECS 214-850-7
p-Bromocinnamic acid
4-BroMocinnaMic acid 5GR
4-Bromocinnamic Acid, Predominantly trans
4-Bromobenzeneacrylic acid

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
344.9±17.0 °C at 760 mmHg

[ Melting Point ]:
260-265 °C

[ Molecular Formula ]:
C₉H₇BrO₂

[ Molecular Weight ]:
227.055

[ Flash Point ]:
162.4±20.9 °C

[ Exact Mass ]:
225.962936

[ PSA ]:
37.30000

[ LogP ]:
3.30

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.648

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UD3110000

CHEMICAL NAME :: 2-Propenoic acid, 3-(4-bromophenyl)-

CAS REGISTRY NUMBER :: 1200-07-3

BEILSTEIN REFERENCE NO. :: 1939350

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H7-Br-O2

MOLECULAR WEIGHT :: 227.07

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >250 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - ataxia Behavioral - rigidity (including catalepsy)

REFERENCE :: IJSIDW Indian Journal of Pharmaceutical Sciences. (Kalina, Santa Cruz (East), Bombay 400 029, India) V.40(2)- 1978- Volume(issue)/page/year: 49,77,1987

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S36/37/39-S26-S22

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
UD3110000

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Stereoselective synthesis of (E)-ß-arylvinyl bromides by microwave-induced reaction of anti-3-aryl-2, 3-dibromopropanoic acids using an AgOAc-AcOH system. Kuang C, et al.

Tetrahedron 61(3) , 637-42, (2005)

A Convenient Synthesis of 1-Amino-7-(Piperidin-4-yl) Isoquinoline. Shkavrov S, et al.

Synth. Commun. 35(5) , 725-30, (2005)

Design, synthesis, and biological evaluation of a dansyled amino acid derivative as an imaging agent for apoptosis. Zeng W, et al.

Tetrahedron Lett. 49(45) , 6429-32, (2008)

Related Compounds

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