AN-12-H5
Names
[ CAS No. ]:
1193340-31-6
[ Name ]:
AN-12-H5
Biological Activity
[Description]:
AN-12-H5 is a bifunctional, enviroxime-like anti-Enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection with EC50 of 0.55 uM; mutations in capsid proteins (G3112A, VP1-Ala224Thr, and G2396A, VP3-Arg227Lys mutations) are resistant to AN-12-H5.
[References]
References 1. Arita M, et al. J Gen Virol. 2010 Nov;91(Pt 11):2734-44. 2. Arita M, et al. J Virol. 2011 Mar;85(5):2364-72. 3. Arita M, et al. J Virol. 2013 Apr;87(8):4252-60. View Related Products by Target Enterovirus
Chemical & Physical Properties
[ Molecular Formula ]:
C24H23N3O4S3
[ Molecular Weight ]:
513.645