Epristeride

Names

[ CAS No. ]:
119169-78-7

[ Name ]:
Epristeride

[Synonym ]:
ONO-9302
Epiristeride
17-n-tert-butylcarboxamide androst-3,5-diene-3-carboxylic acid
(17b)-17-[[(1,1-dimethylethyl)amino]carbonyl]-androsta-3,5-diene-3-carboxylic acid
EPRISTERIDE(SUBJECTTOPATENTFREE)
EPRISTERIDE UV

Biological Activity

[Description]:

Epristeride is a novel 5α-reductase inhibor.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> 5 alpha Reductase

Research Areas >> Cancer

[Target]

5α-reductase[1]

[References]

[1]. Qian LH, et al. Inhibition of regrowth of prostatic glandular cells by epristeride. Acta Pharmacol Sin. 2001 Sep;22(9):847-50.

[Related Small Molecules]

Finasteride | Dutasteride | CGP-53153

Chemical & Physical Properties

[ Density]:
1.13g/cm3

[ Boiling Point ]:
596ºC at 760mmHg

[ Melting Point ]:
242-249°

[ Molecular Formula ]:
C₂₅H₃₇NO₃

[ Molecular Weight ]:
399.56600

[ Flash Point ]:
314.3ºC

[ Exact Mass ]:
399.27700

[ PSA ]:
66.40000

[ LogP ]:
5.49190

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.563

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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