Fmoc-NH-(PEG)9-CH2CH2COOH

Names

[ CAS No. ]:
1191064-81-9

[ Name ]:
Fmoc-NH-(PEG)9-CH2CH2COOH

[Synonym ]:
2,7,10,13,16,19,22,25,28,31-Decaoxa-4-azatetratriacontan-34-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31-decaoxa-4-azatetratriacontan-34-oic acid

Biological Activity

[Description]:

Fmoc-NH-PEG9-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Yang Y,et al. Design, synthesis, and biological characterization of novel PEG-linked dimeric modulators for CXCR4. Bioorg Med Chem. 2016 Nov 1;24(21):5393-5399.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
803.9±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₆H₅₃NO₁₃

[ Molecular Weight ]:
707.805

[ Flash Point ]:
440.0±34.3 °C

[ Exact Mass ]:
707.351685

[ LogP ]:
0.51

[ Vapour Pressure ]:
0.0±3.0 mmHg at 25°C

[ Index of Refraction ]:
1.526

Related Compounds

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