Tizanidine-d4 (hydrochloride)

Names

[ CAS No. ]:
1188263-51-5

[ Name ]:
Tizanidine-d4 (hydrochloride)

[Synonym ]:
Tizanidine-d4 Hydrochloride

Biological Activity

[Description]:

Tizanidine-d4 (hydrochloride) is deuterium labeled Tizanidine (hydrochloride).

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Endocrinology

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

Research Areas >> Neurological Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Kamen L, et al. A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury. Curr Med Res Opin. 2008 Feb;24(2):425-39.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₅D₄Cl₂N₅S

[ Molecular Weight ]:
294.20

[ Exact Mass ]:
293.02100

[ PSA ]:
90.44000

[ LogP ]:
2.35520

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.