3-oxo-C12-aniline
Names
[ CAS No. ]:
1186509-19-2
[ Name ]:
3-oxo-C12-aniline
[Synonym ]:
3-oxo-N-phenyl-Dodecanamide, LasR inhibitor, non-hydrolysable head group
Chemical & Physical Properties
[ Molecular Formula ]:
C18H27NO2
[ Molecular Weight ]:
289.41
[ Storage condition ]:
−20°C
Safety Information
[ RIDADR ]:
NONH for all modes of transport
Articles
J. Am. Chem. Soc. 129(44) , 13613-25, (2007)
Bacteria use a language of low molecular weight ligands to assess their population densities in a process called quorum sensing. This chemical signaling process plays a pivotal role both in the pathog...
Design, synthesis and biological evaluation of abiotic, non-lactone modulators of LuxR-type quorum sensing McInnis CE, and Blackwell HEBioorg. Med. Chem. 19 , 4812-4819, (2011)
Mutational Analysis of the Quorum-Sensing Receptor LasR Reveals Interactions that Govern Activation and Inhibition by Nonlactone Ligands. Gerdt JP, et al.
Chem. Biol. 21 , 1361-1369, (2014)