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Vitexdoin A

Names

[ CAS No. ]:
1186021-77-1

[ Name ]:
Vitexdoin A

[Synonym ]:
(3R,4S)-6,7-Dihydroxy-4-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-3,4-dihydro-2-naphthalenecarbaldehyde
2-Naphthalenecarboxaldehyde, 3,4-dihydro-6,7-dihydroxy-4-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-, (3R,4S)-

Biological Activity

[Description]:

Vitexdoin A is a nitric oxide scavenging lignin. Vitexdoin A inhibits NO production with an IC50 of 0.38 μM in LPS (HY-D1056)-stimulated RAW 264.7 cells[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Zheng CJ, et al. Nitric oxide scavenging lignans from Vitex negundo seeds. J Nat Prod. 2009 Sep;72(9):1627-30.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
612.7±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H18O6

[ Molecular Weight ]:
342.34

[ Flash Point ]:
224.2±25.0 °C

[ Exact Mass ]:
342.110352

[ PSA ]:
107.22000

[ LogP ]:
2.63

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.710

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds