DMAPP

Names

[ Name ]:
DMAPP

[Synonym ]:
DIMETHYLALLYL PYROPHOSPHATE TRIAMMONIUM SALT
Diphosphoric acid, 3-methyl-2-buten-1-yl ester, triammonium salt
Diphosphoric acid, 3-methyl-3-buten-1-yl ester, triammonium salt
IPP
MFCD00189839
D-ERYTHRO-2-TETRADECANOYLAMINO-1-PHENYL-1-PROPANOL
ISOPENTENYL PYROPHOSPHATE TRIAMMONIUM SALT
ISOPENTENYL PYROPHOSPHATE AMMONIUM SALT
dimethylallyl diphosphate

Biological Activity

[Description]:

DMAPP (Dimethylallyl pyrophosphate) triammonium is an isoprenoid precursor. DMAPP triammonium, as an isomer of isopentenyl pyrophosphate (IPP), exists in virtually all life forms[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[In Vitro]

DMAPP triammonium is an isoprenoid precursor. DMAPP triammonium is a product of both the mevalonate pathway and the MEP pathway of isoprenoid precursor biosynthesis. DMAPP triammonium is an isomer of isopentenyl pyrophosphate (IPP) and exists in virtually all life forms. The enzyme isopentenyl pyrophosphate isomerase catalyzes isomerization between DMAPP and IPP[1]

[References]

[1]. Wang W, et al. Bioorganometallic chemistry with IspG and IspH: structure, function, and inhibition of the [Fe(4)S(4)] proteins involved in isoprenoid biosynthesis. Angew Chem Int Ed Engl. 2014;53(17):4294-4310.

Chemical & Physical Properties

[ Boiling Point ]:
550.8ºC at 760 mmHg

[ Molecular Formula ]:
C₅H₂₁N₃O₇P₂

[ Molecular Weight ]:
297.184

[ Flash Point ]:
21ºC

[ Exact Mass ]:
297.085480

[ PSA ]:
141.40000

[ LogP ]:
3.62210

[ Vapour Pressure ]:
1.38E-13mmHg at 25°C

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T

[ Risk Phrases ]:
R10

[ Safety Phrases ]:
S7

[ RIDADR ]:
UN 1230 3/PG 2

Precursor & DownStream

Precursor

DownStream

Articles

Coupling limonene formation and oxyfunctionalization by mixed-culture resting cell fermentation.

Biotechnol. Bioeng. 112 , 1738-50, (2015)

Metabolic engineering strategies mark a milestone for the fermentative production of bulk and fine chemicals. Yet, toxic products and volatile reaction intermediates with low solubilities remain chall...

Cloning and characterization of farnesyl pyrophosphate synthase from the highly branched isoprenoid producing diatom Rhizosolenia setigera.

Sci. Rep. 5 , 10246, (2015)

The diatom Rhizosolenia setigera Brightwell produces highly branched isoprenoid (HBI) hydrocarbons that are ubiquitously present in marine environments. The hydrocarbon composition of R. setigera vari...

Characterization of the xiamenmycin biosynthesis gene cluster in Streptomyces xiamenensis 318.

PLoS ONE 9(6) , e99537, (2014)

Xiamenmycin (1) is a prenylated benzopyran derivative with anti-fibrotic activity. To investigate the genetic basis of xiamenmycin biosynthesis, we performed genome mining in the xiamenmycin-producing...