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13-​cis Acitretin D3

Names

[ CAS No. ]:
1185241-03-5

[ Name ]:
13-​cis Acitretin D3

Biological Activity

[Description]:

13-cis Acitretin D3 （Isoacitretin D3） is a deuterium labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis[1][2].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. A E Stuck, et al. Pharmacokinetics of acitretin and its 13-cis metabolite in patients on haemodialysis. Br J Clin Pharmacol. 1989 Mar; 27(3): 301–304.

[2]. Berbis P, et al. Residual plasma concentrations of acitretin (Ro 10-1670) and its metabolite (Ro 13-7652) after chronic administration. Dermatologica. 1988;177(4):244-6.

Chemical & Physical Properties

[ Melting Point ]:
178-180°C

[ Molecular Formula ]:
C21H23D3O3

[ Molecular Weight ]:
326.42934

[ Storage condition ]:
Amber Vial, -86°C Freezer, Under Inert Atmosphere

Related Compounds

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