Trometamol hydrochloride

Names

[ Name ]:
Trometamol hydrochloride

[Synonym ]:
Tris(hydroxymethyl)aminomethane Hydrochloride
2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride
MFCD00012590
2-Amino-2-(hydroxymethyl)propan-1,3-diolhydrochlorid
2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride (1:1)
TRIS HCl
2-amino-2-(hydroxymethyl)propane-1,3-diol,hydrochloride
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1:1)
tromethamine hydrochloride
Tris(hydroxymethyl)aminomethane hydrochloride(TRIS-HCl)
2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride (1:1)
Tris(hydroxymethyl)aminomethane HCl
Tris(hydroxymethyl)aminometha
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride
TRIS HCl,TRIS hydrochloride,Tris(hydroxymethyl)aminomethane hydrochloride
Tris Hydrochloride
EINECS 214-684-5
Trimethylolaminomethane Hydrochloride
2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride

Biological Activity

[Description]:

Trometamol hydrochloride (Tromethamine hydrochloride) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol hydrochloride is an effective amine compound for pH control in the physiological range[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Nahas GG, et al. Guidelines for the treatment of acidaemia with THAM. Drugs. 1998 Feb;55(2):191-224.

Chemical & Physical Properties

[ Density]:
1.05 g/mL at 20 °C

[ Boiling Point ]:
357ºC at 760 mmHg

[ Melting Point ]:
150-152 °C

[ Molecular Formula ]:
C₄H₁₂ClNO₃

[ Molecular Weight ]:
157.596

[ Flash Point ]:
169.7ºC

[ Exact Mass ]:
157.050568

[ PSA ]:
86.71000

[ Storage condition ]:
Store at RT.

[ Stability ]:
Stable. Incompatible with strong oxidizing agents, bases, moisture.

[ Water Solubility ]:
SOLUBLE

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
TY2900000

[ HS Code ]:
2922199090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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