Pradimicin A

Names

[ Name ]:
Pradimicin A

Biological Activity

[Description]:

Pradimicin A (PRM-A) is a potent antifungal agent, with an MIC of 4 μg/mL against Candida rugosa. Pradimicin A has antiviral activities against CoV, HIV and other enveloped viruses. Pradimicin A shows aggregation property, and can recognize d-Man in the presence of Ca2+ ion[1][2].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

Signaling Pathways >> Anti-infection >> SARS-CoV

[Target]

MIC: 4 μg/mL (Candida rugosa)[1]

[References]

[1]. Miyanishi W, et al. d-Mannose binding, aggregation property, and antifungal activity of amide derivatives of pradimicin A. Bioorg Med Chem. 2021 Dec 27;55:116590.

[2]. Nakagawa Y, Doi T, Masuda Y, Takegoshi K, Igarashi Y, Ito Y. Mapping of the primary mannose binding site of pradimicin A. J Am Chem Soc. 2011 Nov 2;133(43):17485-93.

Chemical & Physical Properties

[ Density]:
1.688g/cm3

[ Boiling Point ]:
1120.269°C at 760 mmHg

[ Molecular Formula ]:
C₄₀H₄₄N₂O₁₈

[ Molecular Weight ]:
840.78

[ Flash Point ]:
631.316°C

[ Exact Mass ]:
840.25900

[ PSA ]:
320.56000

[ LogP ]:
0.17010

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.