G6PI 325-339 (human)

Names

[ CAS No. ]:
1174631-35-6

[ Name ]:
G6PI 325-339 (human)

Biological Activity

[Description]:

G6PI 325-339 (human) is an efficient inducer of arthritis in B10.Q mice. G6PI 325-339 (human) primes Th1 and Th17 cells cross-reacted with the murine G6PI protein. G6PI 325-339 (human) induces arthritis model operating through a T and B cell-dependent pathway but without antibody effector mechanisms[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Angela Pizzolla, et al. A glucose-6-phosphate isomerase peptide induces T and B cell-dependent chronic arthritis in C57BL/10 mice: arthritis without reactive oxygen species and complement. Am J Pathol. 2013 Oct;183(4):1144-1155.  

Chemical & Physical Properties

[ Molecular Formula ]:
C82H117N19O21S3

[ Molecular Weight ]:
1801.12

Related Compounds

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