Xenopsin-Related Peptide 2 (XP-2) trifluoroacetate salt

Names

[ Name ]:
Xenopsin-Related Peptide 2 (XP-2) trifluoroacetate salt

[Synonym ]:
Xenopsin-Related Peptide 2 (XP-2)

Biological Activity

[Description]:

Xenopsin-Related Peptide 2 (XP-2) is an avian counterpart to amphibian Xenopsin (HY-P0253). Xenopsin-Related Peptide 2 displays abilities to release histamine from isolated rat mast cells and is as effective as synthetic Bradykinin (HY-P0206)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[In Vitro]

Synthetic and native preparations of Xenopsin-Related Peptide 2 (XP-2) increases vascular permeability in rats and released histamine from isolated rat mast cells at submicromolar concentrations[1].

[In Vivo]

Xenopsin-Related Peptide 2 (XP-2) (0.3-3000 nM; intradermally; 50 μL) induces skin vascular permeability in rats[1]. Animal Model: Rats weighing 300-400 g[1] Dosage: 0.3-3000 nM Administration: Intradermal injection, 50 μL Result: Increased skin vascular permeability in a dose-dependent manner.

[References]

[1]. Carraway RE, et al. Xenopsin-related peptide generated in avian gastric extracts. Regul Pept. 1988 Sep;22(4):303-14.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₀H₈₈N₁₆O₁₀

[ Molecular Weight ]:
1193.44000

[ Exact Mass ]:
1192.69000

[ PSA ]:
410.93000

[ LogP ]:
5.51880