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Wulignan A1

Names

[ CAS No. ]:
117047-76-4

[ Name ]:
Wulignan A1

[Synonym ]:
(2S,3S,4R)-7-Hydroxy-4-(4-hydroxy-3-methoxyphenyl)-6-methoxy-2,3-dimethyl-3,4-dihydro-1(2H)-naphthalenone
1(2H)-Naphthalenone, 3,4-dihydro-7-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-6-methoxy-2,3-dimethyl-, (2S,3S,4R)-
Wulignan A1
Arisantetralone A
(-)-Arisantetralone

Biological Activity

[Description]:

Wulignan A1 is isolated from the stems of Schisandra henryi. Wulignan A1 exhibits anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Infection

[Target]

IC50: H1N1; H1N1-TR[1]


[References]

[1]. Chang, Wen-liang, Schisandrae fructus extracts for inhibition or prevention of H1N1 influenza virus infection and its application thereof. US 8414938 B2[P]. 2013.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
527.2±50.0 °C at 760 mmHg

[ Melting Point ]:
195-197 °C

[ Molecular Formula ]:
C20H22O5

[ Molecular Weight ]:
342.386

[ Flash Point ]:
187.1±23.6 °C

[ Exact Mass ]:
342.146729

[ PSA ]:
75.99000

[ LogP ]:
3.46

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.583


Related Compounds

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