Ramatercept

Names

[ CAS No. ]:
1169766-01-1

[ Name ]:
Ramatercept

Biological Activity

[Description]:

Ramatercept is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy[1][2][3].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

soluble activin receptor 2, ACVR2[2]


[In Vivo]

Ramatercept (10 mg/kg；皮下注射；每周 3 次，持续 5 周) 显著增加了小鼠的肌肉量[1]。

[References]

[1]. Fariello R G, et al. A novel Biological (FOX-115) improves endurance of motor performances in old mice (P2. 4-033)[J]. 2019.

[2]. Feike Y, et al. Advances in research on pharmacotherapy of sarcopenia. Aging Med (Milton). 2021 Aug 9;4(3):221-233.  

[3]. Louvel É. Dopage: nouveaux médicaments influant sur la biogenèse musculaire et mitochondriale[J]. 2019.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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