Biotin-PEG5-azide

Names

[ Name ]:
Biotin-PEG5-azide

[Synonym ]:
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(17-azido-3,6,9,12,15-pentaoxaheptadec-1-yl)hexahydro-2-oxo-, (3aS,4S,6aR)-
N-(17-Azido-3,6,9,12,15-pentaoxaheptadec-1-yl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
MFCD22683275

Biological Activity

[Description]:

Biotin-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₄₀N₆O₇S

[ Molecular Weight ]:
532.654

[ Exact Mass ]:
532.267944

[ LogP ]:
-1.64

[ Storage condition ]:
2-8°C

Related Compounds

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