TC-I 2000

Names

[ CAS No. ]:
1159996-20-9

[ Name ]:
TC-I 2000

[Synonym ]:
sb 611812

Biological Activity

[Description]:

TRPM8-IN-1 (example 14) is an inhibitor of transient receptor potential melastatin-8 (TRPM8) channels, IC50<5 μM[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Neurological Disease

[Target]

TRPM8:<5 μM (IC50)

[References]

[1]. Norman, et al. Preparation of substituted dihydroisoquinoline derivatives for use as TRP-M8 receptor ligands. World Intellectual Property Organization, WO2009073203 A1. 2009-06-11.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₁₈F₄N₂O

[ Molecular Weight ]:
414.39500

[ Exact Mass ]:
414.13600

[ PSA ]:
32.34000

[ LogP ]:
6.03500

Related Compounds

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