Angoroside C

Names

[ Name ]:
Angoroside C

[Synonym ]:
β-D-Glucopyranoside, 2-(3-hydroxy-4-methoxyphenyl)ethyl O-α-L-arabinopyranosyl-(1->6)-O-[6-deoxy-α-L-talopyranosyl-(1->3)]-4-O-[(2E)-3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propen-1-yl]-
2-(3-Hydroxy-4-methoxyphenyl)ethyl α-L-arabinopyranosyl-(1->6)-[6-deoxy-α-L-talopyranosyl-(1->3)]-4-O-[(2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoyl]-β-D-glucopyranoside
Angoroside C
2-(3-Hydroxy-4-methoxyphenyl)ethyl α-L-arabinopyranosyl-(1->6)-[6-deoxy-α-L-talopyranosyl-(1->3)]-4-O-[(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]-β-D-glucopyranoside
Angoroside

Biological Activity

[Description]:

Angoroside C, a phenylpropanoid glycoside isolated from Radix Scrophulariae, has beneficial effects against ventricular remodeling[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[In Vivo]

Angoroside C has beneficial effects against ventricular remodeling. The mechanism is likely to be related to decreasing the level of Ang Ⅱ, attenuating the mRNA expressions of ET-1 and TGF-β1[1].

[References]

[1]. Gu WL, et al. The effect of angoroside C on pressure overload-induced ventricular remodeling in rats. Phytomedicine. 2015 Jul 15;22(7-8):705-12.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
985.7±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₆H₄₈O₁₉

[ Molecular Weight ]:
784.755

[ Flash Point ]:
301.7±27.8 °C

[ Exact Mass ]:
784.278992

[ PSA ]:
282.21000

[ LogP ]:
2.66

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.652

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds

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