PAF-AN-1

Names

[ CAS No. ]:
115621-84-6

[ Name ]:
PAF-AN-1

Biological Activity

[Description]:

PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Cardiovascular Disease
Research Areas >> Inflammation/Immunology

[In Vitro]

PAF-AN-1 is extracted from patent EP0469477A1, page 2, line 47[1]. PAF-AN-1 is a 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline analog. PAF-AN-1 inhibits PAF-induced bronchoconstriction and hemoconcentration when administered po to the guinea pig[2].

[References]

[1]. EP0469477A1

[2]. Houlihan WJ, et al. Structural modification of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline platelet activating factor receptor antagonists. J Med Chem. 1993 Oct 15;36(21):3098-102.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Molecular Formula ]:
C28H28N2O3

[ Molecular Weight ]:
440.53

Related Compounds