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Propiophenone, 3-piperidino-4'-propoxy-, hydrochloride

Names

[ CAS No. ]:
1155-49-3

[ Name ]:
Propiophenone, 3-piperidino-4'-propoxy-, hydrochloride

[Synonym ]:
3-piperidin-1-yl-1-(4-propoxyphenyl)propan-1-one,hydrochloride

Chemical & Physical Properties

[ Density]:
1.027g/cm3

[ Boiling Point ]:
411.4ºC at 760mmHg

[ Molecular Formula ]:
C17H26ClNO2

[ Molecular Weight ]:
311.84700

[ Flash Point ]:
202.6ºC

[ Exact Mass ]:
311.16500

[ PSA ]:
29.54000

[ LogP ]:
4.27400

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UH4420000
CHEMICAL NAME :
Propiophenone, 3-piperidino-4'-propoxy-, hydrochloride
CAS REGISTRY NUMBER :
1155-49-3
LAST UPDATED :
199009
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C17-H25-N-O2.Cl-H
MOLECULAR WEIGHT :
311.89
WISWESSER LINE NOTATION :
T6NTJ A2VR DO3 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 31,21,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
57 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 5,559,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
15 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Behavioral - muscle contraction or spasticity Behavioral - irritability
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 115,419,1955

Related Compounds

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