(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin trifluoroacetate salt

Names

[ Name ]:
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin trifluoroacetate salt

[Synonym ]:
L-Ornithine, N-[2-(2-thioxocyclohexyl)acetyl]-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-, methyl ester
des-4-fluoro-benzyl-mosapride
M-1 Cpd
desGly-NH2(9),d(CH2)5[Tyr(Me)2,Thr4]OVT
4-Amino-5-chloro-2-ethoxy-N-((2-morpholinyl)methyl)benzamide
Benzamide,4-amino-5-chloro-2-ethoxy-N-(2-morpholinylmethyl)
Methyl N-[(2-thioxocyclohexyl)acetyl]-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithinate

Biological Activity

[Description]:

(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> GPCR/G Protein >> Oxytocin Receptor

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C₄₅H₆₉N₉O₁₂S₂

[ Molecular Weight ]:
992.21

[ Exact Mass ]:
991.450684

[ PSA ]:
423.60000

[ LogP ]:
1.11

[ Index of Refraction ]:
1.615

Related Compounds

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