Luteolinidin chloride

Names

[ Name ]:
Luteolinidin chloride

[Synonym ]:
luteolinidin
2-(3,4-dihydroxyphenyl)chromenylium-5,7-diol,chloride
deoxyanthocyanidin
3',4',5,7-tetrahydroxyflavylium chloride
MFCD00016779

Biological Activity

[Description]:

Luteolinidin is a natural deoxyanthocyanidin, isolated from mosses and ferns[1]. Luteolinidin is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo[2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Target]

Ki: 11 μM (CD 38)[2]

[References]

[1]. Maria JoãoMelo, et al. Photochemistry of luteolinidin: “Write-lock-read-unlock-erase” with a natural compound. Journal of Photochemistry and Photobiology A: Chemistry

[2]. Boslett J, et al. Luteolinidin Protects the Postischemic Heart through CD38 Inhibition with Preservation of NAD(P)(H). J Pharmacol Exp Ther. 2017 Apr;361(1):99-108.

Chemical & Physical Properties

[ Density]:
1.530 g/mL at 25 °C(lit.)

[ Boiling Point ]:
229-230 °C(lit.)

[ Molecular Formula ]:
C₁₅H₁₁ClO₅

[ Molecular Weight ]:
306.69800

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
306.03000

[ PSA ]:
94.06000

[ LogP ]:
0.20730

[ Index of Refraction ]:
n20/D 1.4760(lit.)

Safety Information

[ Hazard Codes ]:
C

[ Risk Phrases ]:
R34:Causes burns.

[ Safety Phrases ]:
S26-S36/37/39-S45-S39-S37-S36

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2907299090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2907299090

[ Summary ]:
2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

Related Compounds

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