N-Cbz-glycine Ethyl Ester
Names
[ CAS No. ]:
1145-81-9
[ Name ]:
N-Cbz-glycine Ethyl Ester
[Synonym ]:
Ethyl 2-(((benzyloxy)carbonyl)amino)acetate
ethyl 2-(phenylmethoxycarbonylamino)acetate
Z-Gly-Gly-Oet
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
502.1±40.0 °C at 760 mmHg
[ Melting Point ]:
81-82℃
[ Molecular Formula ]:
C14H18N2O5
[ Molecular Weight ]:
294.303
[ Flash Point ]:
257.4±27.3 °C
[ Exact Mass ]:
294.121582
[ PSA ]:
93.73000
[ LogP ]:
1.42
[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C
[ Index of Refraction ]:
1.524
[ Storage condition ]:
2-8°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MB9134000
- CHEMICAL NAME :
- Glycine, N-carboxy-, N-benzyl ester, ethyl ester
- CAS REGISTRY NUMBER :
- 1145-81-9
- BEILSTEIN REFERENCE NO. :
- 2219244
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C12-H15-N-O4
- MOLECULAR WEIGHT :
- 237.28
- WISWESSER LINE NOTATION :
- 2OV1MVO1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 280 mg/kg
- SEX/DURATION :
- female 28 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 70,60,1981
Safety Information
[ Hazard Codes ]:
Xi
[ HS Code ]:
2924299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%