AZD-5363

Names

[ CAS No. ]:
1143532-51-7

[ Name ]:
AZD-5363

[Synonym ]:
10668
MFCD22628785
4-Piperidinecarboxamide, 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-
AZD-5363
4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(1H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinecarboxamide
capivasertib
WFR23M21IE

Biological Activity

[Description]:

(R)-Capivasertib ((R)-AZD5363) is the R-enantiomer of Capivasertib (HY-15431)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Davies BR, et al. Preclinical pharmacology of AZD5363, an inhibitor of AKT: pharmacodynamics, antitumor activity, and correlation of monotherapy activity with genetic background. Mol Cancer Ther. 2012 Apr;11(4):873-87.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C21H25ClN6O2

[ Molecular Weight ]:
428.915

[ Exact Mass ]:
428.172760

[ LogP ]:
1.04

[ Index of Refraction ]:
1.670