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Puerarin 6''-O-xyloside

Names

[ CAS No. ]:
114240-18-5

[ Name ]:
Puerarin 6''-O-xyloside

[Synonym ]:
(1S)-1,5-Anhydro-1-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]-6-O-β-D-xylopyranosyl-D-glucitol
D-Glucitol, 1,5-anhydro-1-C-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-8-yl]-6-O-β-D-xylopyranosyl-, (1S)-
Puerarin 6''-O-xyloside

Biological Activity

[Description]:

Puerarin 6''-O-Xyloside, isolated from radix of Pueraria lobata (Willd.), possesses snti-osteoporotic and anti-tumor activity. Puerarin 6''-O-Xyloside induces the mitochondria-mediated apoptosis pathway.[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Research Areas >> Inflammation/Immunology

[References]

[1]. Li H, et al. Anti-osteoporotic activity of puerarin 6"-O-xyloside on ovariectomized mice and its potential mechanism. Pharm Biol. 2016;54(1):111-7.

[2]. Chen T, et al. In vitro and in vivo antitumour activities of puerarin 6″-O-xyloside on human lung carcinoma A549 cell line via the induction of the mitochondria-mediated apoptosis pathway. Pharm Biol. 2016 Sep;54(9):1793-9.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
833.0±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H28O13

[ Molecular Weight ]:
548.493

[ Flash Point ]:
280.6±27.8 °C

[ Exact Mass ]:
548.153015

[ LogP ]:
1.48

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.746

Related Compounds