Z-LEED-FMK

Names

[ CAS No. ]:
1135688-38-8

[ Name ]:
Z-LEED-FMK

Biological Activity

[Description]:

Z-LEED-FMK is a caspase-13 and caspase-4 inhibitor. Z-LEED-FMK also inhibits caspase-1 processing in S. typhimurium-infected macrophages[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Caspase
Research Areas >> Inflammation/Immunology

[Target]

Caspase-13

Caspase-4

Caspase-1


[References]

[1]. Asch R J, et al. Role of Individual Amino Acids in the Action of Caspase Inhibitors as Proapoptotic Peptides for Human Leukemia. 2004.

[2]. Imamura R, et al. Anti-inflammatory activity of PYNOD and its mechanism in humans and mice. J Immunol. 2010 May 15;184(10):5874-84.  

Chemical & Physical Properties

[ Molecular Formula ]:
C32H45FN4O12

[ Molecular Weight ]:
696.72

Related Compounds

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