Dichloro(diphenyl)stannane
Names
[ CAS No. ]: 
1135-99-5
        
[ Name ]: 
Dichloro(diphenyl)stannane
        
[Synonym ]:
                
                MFCD00000516
                
                
            
                
                Dichloro(diphenyl)stannane
                
                
            
                
                Stannane, dichlorodiphenyl-
                
                
            
                
                EINECS 214-496-3
                
                
                
                
    
Chemical & Physical Properties
[ Boiling Point ]:
330.7±25.0 °C at 760 mmHg
            
[ Melting Point ]:
41-43 °C(lit.)
            
[ Molecular Formula ]:
C12H10Cl2Sn
            
[ Molecular Weight ]:
343.824
            
[ Flash Point ]:
153.8±23.2 °C
            
[ Exact Mass ]:
343.918152
            
[ LogP ]:
9.01
            
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
            
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
 - WH7253000
 
- CHEMICAL NAME :
 - Stannane, dichlorodiphenyl-
 
- CAS REGISTRY NUMBER :
 - 1135-99-5
 
- LAST UPDATED :
 - 199712
 
- DATA ITEMS CITED :
 - 27
 
- MOLECULAR FORMULA :
 - C12-H10-Cl2-Sn
 
- MOLECULAR WEIGHT :
 - 343.81
 
- WISWESSER LINE NOTATION :
 - G-SN-GR&R
 
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
 - LDLo - Lowest published lethal dose
 
- ROUTE OF EXPOSURE :
 - Oral
 
- SPECIES OBSERVED :
 - Rodent - rat
 
- DOSE/DURATION :
 - 410 mg/kg
 
- TOXIC EFFECTS :
 - Behavioral - muscle weakness Lungs, Thorax, or Respiration - chronic pulmonary edema Lungs, Thorax, or Respiration - dyspnea
 
- TYPE OF TEST :
 - LDLo - Lowest published lethal dose
 
- ROUTE OF EXPOSURE :
 - Oral
 
- SPECIES OBSERVED :
 - Rodent - mouse
 
- DOSE/DURATION :
 - 470 mg/kg
 
- TOXIC EFFECTS :
 - Details of toxic effects not reported other than lethal dose value
 
- TYPE OF TEST :
 - LD50 - Lethal dose, 50 percent kill
 
- ROUTE OF EXPOSURE :
 - Intraperitoneal
 
- SPECIES OBSERVED :
 - Rodent - mouse
 
- DOSE/DURATION :
 - 17800 ug/kg
 
- TOXIC EFFECTS :
 - Details of toxic effects not reported other than lethal dose value
 
MUTATION DATA
- TYPE OF TEST :
 - Sex chromosome loss and nondisjunction
 
- TEST SYSTEM :
 - Human Lymphocyte
 
- REFERENCE :
 - MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 246,109,1991 *** REVIEWS *** ACGIH TLV-TWA 0.1 mg(Sn)/m3;STEL 0.2 mg/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.1 mg(Sn)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,258,1971 OSHA PEL (Gen Indu):8H TWA 0.1 mg(Sn)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.1 mg(Sn)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.1 mg(Sn)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.1 mg(Sn)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.1 mg(Sn)/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.1 mg(Sn)/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.1 mg(Sn)/m3;Skin JAN 1993 OEL-FINLAND:TWA 0.1 mg(Sn)/m3;STEL 0.3 mg(Sn)/m3;Skin JAN 1993 OEL-FRANCE:TWA 0.1 mg(Sn)/m3;STEL 0.2 mg(Sn)/m3 JAN 1993 OEL-GERMANY:TWA 0.1 mg(Sn)/m3;Skin JAN 1993 OEL-HUNGARY:STEL 0.1 mg(Sn)/m3;Skin JAN 1993 OEL-THE NETHERLANDS:TWA 0.1 mg(Sn)/m3;Skin JAN 1993 OEL-THE PHILIPPINES:TWA 0.1 mg(Sn)/m3 JAN 1993 OEL-SWEDEN:TWA 0.1 mg(Sn)/m3;STEL 0.2 mg(Sn)/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg(Sn)/m3;STEL 0.2 mg(Sn)/m3;Skin JAN 1993 OEL-THAILAND:TWA 0.1 mg(Sn)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg(Sn)/m3;STEL 0.2 mg(Sn)/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO ORGANOTIN COMPOUND-air:10H TWA 0.1 mg(Sn)/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992
 
Safety Information
[ Symbol ]:
                
                
                GHS07, GHS09
            
[ Signal Word ]: 
Warning
            
[ Hazard Statements ]:
 H302 + H312 + H332-H315-H319-H335-H400
            
[ Precautionary Statements ]:
 P261-P273-P280-P305 + P351 + P338
            
[ Personal Protective Equipment ]:
 dust mask type N95 (US);Eyeshields;Gloves
            
[ Hazard Codes ]:
 Xn:Harmful;
            
[ Risk Phrases ]:
 R20/21/22;R36/37/38
            
[ Safety Phrases ]:
 S26-S37/39
            
[ RIDADR ]: 
UN 3146 6.1/PG 3
            
[ WGK Germany ]: 
3
            
[ RTECS ]: 
WH7253000
            
[ Packaging Group ]:
 III
            
[ Hazard Class ]:
6.1
            
[ HS Code ]:
 2931900090
            
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2931900090
[ Summary ]: 
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
            
Articles
ScientificWorldJournal 2013 , 106357, (2014)
The interaction of 3,3-bis(1-methylimidazol-2-yl)propionate (BIMP) with dimethyltin(IV) dichloride (DMT), dibutyltin(IV) dichloride (DBT), and diphenyltin(IV) dichloride (DPT) is investigated at 25°C ...
The proteasome is a molecular target of environmental toxic organotins.Environ. Health Perspect. 117 , 379-86, (2009)
Because of the vital importance of the proteasome pathway, chemicals affecting proteasome activity could disrupt essential cellular processes. Although the toxicity of organotins to both invertebrates...
New approach of solid-phase microextraction improving the extraction yield of butyl and phenyltin compounds by combining the effects of pressure and type of agitation.J. Chromatogr. A. 1072(1) , 19-27, (2005)
A new methodology for the simultaneous and fast solid-phase microextraction (SPME) of butyl- and phenyltin compounds, as ethylated derivates, is proposed in this paper. The effects of pressure and typ...