2,3-Difluorobenzyl bromide

Names

[ Name ]:
2,3-Difluorobenzyl bromide

[Synonym ]:
FR BF C1E
Benzene, 1-(bromomethyl)-2,3-difluoro-
α-Bromo-2,3-difluorotoluene
2,3-Difluoro benzyl bromide
MFCD00042488
1-(Bromomethyl)-2,3-difluorobenzene

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
190.5±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C₇H₅BrF₂

[ Molecular Weight ]:
207.015

[ Flash Point ]:
69.0±23.2 °C

[ Exact Mass ]:
205.954269

[ LogP ]:
2.93

[ Vapour Pressure ]:
0.7±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.523

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S25

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2903999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Evaluation of a series of bicyclic CXCR2 antagonists.

Bioorg. Med. Chem. Lett. 18(2) , 798-803, (2008)

The CXCR2 SAR of a series of bicyclic antagonists such as the 2-aminothiazolo[4,5-d]pyrimidine 3b was investigated by systematic variation of the fused pyrimidine-based heterocyclic cores. Replacement...