3-Hydroxy-4-methoxyphenylacetic acid

Names

[ Name ]:
3-Hydroxy-4-methoxyphenylacetic acid

[Synonym ]:
(3-Hydroxy-4-methoxyphenyl)acetic acid
MFCD00016829
Benzeneacetic acid, 3-hydroxy-4-methoxy-
2-(3-hydroxy-4-methoxyphenyl)acetic acid
3-Hydroxy-4-methoxybenzeneacetic acid
Homoisovanillic acid
QV1R CQ DO1
3-Hydroxy-4-methoxyphenylacetic acid

Biological Activity

[Description]:

Isohomovanillic acid (3-Hydroxy-4-methoxyphenylacetic acid) is extracted from urine at pH 2 by ethyl acetate. Isohomovanillic acid is not found in appreciable values in many normal human urines[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Human Endogenous Metabolite

[References]

[1]. Comoy E, et al. Iso-homovanillic acid determination in human urine. Clin Chim Acta. 1971 Dec;35(2):369-75.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
371.3±27.0 °C at 760 mmHg

[ Melting Point ]:
128 °C

[ Molecular Formula ]:
C₉H₁₀O₄

[ Molecular Weight ]:
182.173

[ Flash Point ]:
153.1±17.2 °C

[ Exact Mass ]:
182.057907

[ PSA ]:
66.76000

[ LogP ]:
0.47

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.573

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi,Xn

[ Risk Phrases ]:
22-36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Determination of 4-O-methylated catecholamine metabolites in urine by mass fragmentography.

Clin. Chem. 25(10) , 1708-13, (1979)

We describe the determination of the 4-O-methylated catecholamine metabolites 4-methoxy-3-hydroxyphenylacetic acid (iso-HVA), 4-methoxy-3-hydroxyphenylmandelic acid (iso-VMA) and 4-methoxy-3-hydroxyph...

Levels of dopamine and 3,4-dihydroxyphenylacetic acid in the adenohypophysis of normo- and hypertensive rats.

Clin. Exp. Hypertens. A. 12(3) , 343-53, (1990)

The levels of dopamine and its metabolites in the adenohypophysis of the normo- and hypertensive rats were determined. Dopamine was present as the free and sulfate-conjugated form in the adenohypophys...

Determination of homovanillic, isohomovanillic and vanillylmandelic acids in human urine by means of glass capillary gas-liquid chromatography with temperature-programmed electron-capture detection.

J. Chromatogr. A. 183(4) , 391-401, (1980)

The determination of urinary homovanillic, isohomovanillic and vanillylmandelic acids as their trifluoroacetylhexafluoroisopropyl ester derivatives by glass capillary gas-liquid chromatography has bee...

Related Compounds

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