4-(2',4'-Difluoro-[1,1'-biphenyl]-4-yl)-2-methyl-4-oxobutanoic acid
Names
[ CAS No. ]:
112344-52-2
[ Name ]:
4-(2',4'-Difluoro-[1,1'-biphenyl]-4-yl)-2-methyl-4-oxobutanoic acid
[Synonym ]:
4-(2',4'-difluorobipenyl-4-yl)-2-methyl-4-oxobutyric acid
3-(4-(2,4-Difluorophenyl)benzoyl)-2-methylpropionic acid
4-(2',4'-difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic acid
rac-flobufen
[1,1'-Biphenyl]-4-butanoicacid,2',4'-difluoro-a-methyl-g-oxo
4-(2',4'-Difluorobiphenylyl)-4-oxo-2-methylbutanoic acid
4-(2',4'-Difluorbiphenyl-4-yl)-2-methyl-4-oxobutansaeure [German]
Flobufen
Chemical & Physical Properties
[ Density]:
1.272g/cm3
[ Boiling Point ]:
456.5ºC at 760mmHg
[ Molecular Formula ]:
C17H14F2O3
[ Molecular Weight ]:
304.28800
[ Flash Point ]:
229.9ºC
[ Exact Mass ]:
304.09100
[ PSA ]:
54.37000
[ LogP ]:
3.92530
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DV1758000
- CHEMICAL NAME :
- (1,1'-Biphenyl)-4-butanoic acid, 2',4'-difluoro-alpha-methyl-gamma-oxo-
- CAS REGISTRY NUMBER :
- 112344-52-2
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C17-H14-F2-O3
- MOLECULAR WEIGHT :
- 304.31
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 134 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 14,24,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 414 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 47,648,1997
Safety Information
[ Hazard Codes ]:
Xn